Human Healthspan Intelligence OS
BH Protocol™
Nine Physiological Axes. One Longitudinal Score. Five Care Phases. Powered by 114 evidence-anchored biomarkers.
The Framework
Nine Physiological Axes
Each axis aggregates validated biomarkers into an axis score. The nine axis scores resolve into the platform’s trajectory-guidance scores — the Longevity Anchor Index™ (LAI™), the L²AI™ Coherence score and the Health Coherence Index™ (HCI™). The scores guide the journey; the axes are the physiology.
Mitochondrial & Cell Health
VO₂ max, cardiac output, mitochondrial energy production, HRV. The energetic engine of biological health at cell level.
Neuro-Hormonal & Cognitive
Homocysteine, thyroid function (TSH/FT4), cognitive performance, mood and stress resilience. Brain and neuro-hormonal vitality.
Cardiovascular & Metabolic
ApoB, LDL-C, HbA1c, fasting insulin, HOMA-IR, uric acid, thyroid function. The most causally established axis for longevity outcomes.
Immune-Metabolic Axis
hsCRP, full blood count, neutrophil:lymphocyte ratio. Inflammaging and immune-metabolic cross-talk — a central driver of biological aging.
Musculoskeletal & Energy
Grip strength, gait speed, sit-to-rise test, body composition (DEXA). Functional reserve and sarcopenia prevention.
Gut & Immune System
Dietary fibre, plant diversity, microbiome sequencing. The gut–brain–immune connection.
Circadian Rhythm & Sleep
Sleep architecture and REM quality, sleep-timing regularity, cortisol rhythm — and the hormonal panel: thyroid (TSH/FT4), testosterone, oestrogen, progesterone, DHEA-S, vitamin D. The body’s master clock and hormonal home. Key hormones such as thyroid also feature on the metabolic and cognitive axes.
Detoxification & Function Health
Hepatic and renal biomarkers — ALT/AST, FIB-4 index, eGFR — alongside functional health measures. Clearance capacity, organ function and physiological reserve.
Bio-Coherence Communication
Cross-axis signal integration — how coherently the eight physiological systems communicate and function as one. The integrative axis of the framework.
Clinical Application
BH Protocol™ Five Care Phases
The LAI™ score places every patient in a defined care phase — and each phase carries its own clinical posture, monitoring frequency and intervention intensity.
Reconcile
Active medical management. Biological conflict resolution. BH Protocol™ captures the biological nadir.
Restore
Post-crisis stabilisation. Protect mitochondrial reserve. Conservative intervention. High-frequency monitoring.
Recharge
Active biological recovery. Drive multi-axis improvement. Full protocol activation. Maximum intervention window.
Resilience
Optimised healthspan maintenance. Biological systems coherent. Sustain gains. Prevent regression.
Rejuvenate
Active biological age reversal. Epigenetic clock regression. Elite longevity medicine.
Clinical Evidence
N=1 Index Case
Unedited longitudinal data from the BH Protocol™ index case — precision lifestyle medicine integrated with judicious, clinician-directed care.
N=1 Index Case: Founder applied himself as a documented medical case profile — 27 months of continuous clinical observation with serial biomarker panels across 4 timepoints — forming the clinical foundation and design architecture of the Healthspan Intelligence engine. Unedited real data. Provisional Patent #1 — BH Protocol™ Human HealthSpan OS, SG IPOS · USPTO · WIPO PCT.
A single-subject longitudinal dataset is a proof of concept, not a controlled trial. Results are not generalisable and do not constitute evidence of efficacy in any other individual.
Full Health Intelligence Report™
The complete longitudinal report and the AURUM™ LifeApp v7 environment are available to registered clinicians, partners and research collaborators only. Access is issued individually after registration.
Intellectual Property
Provisional Patent #1
BH Protocol™ Human HealthSpan Operating System. Filed SG IPOS · USPTO · WIPO PCT. Invented by Dr Billy Hardie, MBBS. Held by Ark Active Pte Ltd, UEN 201322195G.
Your health, on the BH Protocol™
Registration is free. Your clinician-governed health intelligence starts the day you join.